150+ biscuits. Biscuits for dogs over 50 lbs. Helps clean teeth & freshens breath. 12 vitamins & minerals. Loved since 1908. You're Giving More than Just a Healthy & Tasty Treat: The makers of Milk-Bone dog snacks believe in giving back. That's why since 1997, a portion of every Milk-Bone dog snacks purchase goes towards providing service dogs to children and adults with physical disabilities and special needs. Visit milkbone.com to see how you can help us change the lives of others in need. Calorie Content (calculated): Metabolizable Energy (ME) 3190 kcal/kg; 125 kcal/biscuit. If you have any questions about Milk-Bone dog snacks, please call 1-888-Milkbone (645-5266), weekdays. Please include the product manufacturing code in consumer correspondence. Produced in Buffalo New York, USA.